Weight loss is a huge topic right now. According to the World Health Organisation, 1 in 8 people were obese in 2022 and adult obesity has more than doubled in the last three decades[i]. This increasing burden signifies that support needs to be put in place for individuals to help them manage their weight.
With the approval of type 2 diabetes medicines like Wegovy and Saxenda for obesity, the world of medicine is recognising that more needs to be done to aid weight loss alongside typical diet and exercise changes.
Although FDA-approved and highly effective, these medicines are reserved for the most severe cases and can cause some nasty side effects. So, what’s the alternative?
Here we introduce FullnessFactor BeanPro™ Weight Control Blend. A US-patented combination of natural bean-derived compounds that have been specifically chosen for their weight management properties.
Comprising of a trypsin and an amylase inhibitor naturally derived from pinto beans, join us as we explore what FullnesFactor BeanPro™ Weight Control Blend is, its important benefits, and why you should be seriously considering adding it to your expanding product list.
What is FullnesFactor BeanPro™ Weight Control Blend?
The FullnesFactor BeanPro™ is a combination of natural bean-derived products that are known to help with weight loss. It contains a trypsin inhibitor and an amylase inhibitor. Together, these compounds work to reduce food intake and keep you feeling fuller for longer.
Both compounds are naturally found in some specific beans and legumes, such as soybeans, pinto beans, white kidney beans, and chickpeas.
Next, we’ll explore how these work in more detail.
How does FullnesFactor BeanPro™ Weight Control Blend work?
FullnesFactor BeanPro™ Weight Control Blend works by inhibiting two important enzymes involved in digestion, trypsin and amylase.
Trypsin is an enzyme that is secreted by the pancreas in its inactive form, trypsinogen. Once, it enters the small intestine it is ‘activated’ and becomes trypsin. It works by breaking down protein, alongside two other digestive enzymes pepsin and chymotrypsin, into peptides and amino acids[ii].
Amylase, on the other hand, is a digestive enzyme that is secreted by the salivary glands in your mouth and by your pancreas, to break down complex carbohydrates into simple sugars[iii].
The trypsin and amylase inhibitors in the FullnesFactor BeanPro™ are 100% natural and derived from pinto beans, so you can be sure that you are offering your customers clean ingredients, free from unnecessary additives.
Shi et al., (2017) investigated the effects of processing different types of beans on inhibitors of α-amylase, trypsin, and chymotrypsin. Their results found that both α-amylase and trypsin inhibition were high in beans, with soybeans having the highest level of trypsin inhibitory activity[iv].
How does a trypsin inhibitor aid weight loss?
The FullnesFactor BeanPro™ Weight Control Blend contains a natural bean-derived trypsin inhibitor that is found in beans and legumes. It inhibits the action of trypsin, which slows down protein digestion, increasing the feeling of fullness.
A 2015 study evaluated the effect of naturally derived trypsin inhibitor from Tamarindus indica L. seeds on weight and food intake. In rat models, the trypsin inhibitor lowered food consumption, reducing weight gain[v].
So, trypsin inhibitors may aid weight loss through their capacity to lower the amount of food a person is eating. However, care must be taken because taking too many trypsin inhibitors can lead to an irreversible trypsin enzyme-trypsin inhibitor complex which may interfere with the digestion of proteins[vi].
How do amylase inhibitors help weight loss?
The inhibition of amylase enzymes in the digestion process can help to slow digestion and the absorption of carbohydrates which can have profound metabolic effects, including:
- Regulating blood sugar levels
- Reducing cravings
- Increasing a sense of fullness, preventing overeating
A review of 14 studies by Udani et al., (2018) found that supplementation of an amylase inhibitor extracted from white beans showed an average weight loss of -1.08 kg. The review also found an average body fat reduction of 3.26 kg when the natural amylase inhibitor was taken[vii].
A double-blind, placebo-controlled study involving 101 volunteers with a body mass index (BMI) between 25 and 40 was divided into a placebo and active substance group. Those in the latter group received two capsules containing a natural bean-derived amylase inhibitor 15 minutes before each of their meals for 60 days. After 60 days, 51 participants lost an average of 1.9 kg of body weight compared to 0.4 kg in the placebo group[viii].
Wang et al., (2021) investigated the effect of white bean-derived amylase inhibitors on blood glucose levels in hyperglycaemic mice. The mice were split into 5 groups and fed for 8 weeks and fed for 8 weeks with standard chow diets, high-fat diets, or high-fat diets with a supplement of an α-amylase inhibitor in white kidney beans (PVE), yogurt (Y) and the α-amylase inhibitor added to yogurt (YPVE).
The results found that in mice fed a high-fat diet, PVE, Y, and YPVE reduced blood sugar, insulin, blood fats and inflammatory cytokine levels. The YPVE intervention also modulated the gut bacteria towards a healthy pattern[ix].
Why health and fitness businesses should add FullnesFactor BeanPro™ Weight Control Blend to their offering
There is an increasing interest in the weight loss supplements market. In 2020, the global weight loss supplements market was valued at USD 33.4 billion and is expected to expand at a compound annual growth rate of 16.6% between 2021 and 2028[x].
With obesity being a global health problem there is a trend towards managing obesity with natural compounds, especially as some of the anti-obesity medications can have both varying outcomes and side effects. The FullnesFactor BeanPro™ from Stockk Nutrition offers a unique and patented alternative[xi].
The Weight Control Blend offers a scientifically backed solution for appetite control and weight management. It is available in several forms:
- Capsules
- Tablets
- RTD powder mix
The US-patented blend is intended to reduce overall food intake by promoting a feeling of satiety following a meal, assisting in weight loss efforts. The natural bean-derived digestive enzyme inhibitors are from common beans.
Summary
The FullnesFactor BeanPro™ offers an alternative to weight loss medications using natural ingredients from beans to help inhibit some of the key digestive enzymes. In doing so, their activity is reduced helping the individual to feel fuller for longer, reducing food cravings, and helping to maintain blood sugar levels.
If the FullnesFactor BeanPro™ supplement is something you think your consumers would benefit from, get in touch with the Stockk Nutrition team today to find out how you can partner with use.
Written by: Leanne Edermaniger MSC.
Sources
[i] Obesity and overweight [Internet]. World Health Organization; [cited 2024 Mar 4]. Available from: https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight
[ii] Vertiprakhov VG, Ovchinnikova NV. The activity of trypsin in the pancreatic juice and blood of poultry increases simultaneously in the postprandial period. Front Physiol. 2022 Oct 25;13:874664. doi: 10.3389/fphys.2022.874664. PMID: 36388123; PMCID: PMC9641294.
[iii] Akinfemiwa O, Zubair M, Muniraj T. Amylase. [Updated 2023 Nov 12]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK557738/
[iv] Shi L, Mu K, Arntfield SD, Nickerson MT. Changes in levels of enzyme inhibitors during soaking and cooking for pulses available in Canada. J Food Sci Technol. 2017 Mar;54(4):1014-1022. doi: 10.1007/s13197-017-2519-6. Epub 2017 Feb 9. PMID: 28303052; PMCID: PMC5336459.
[v] Ribeiro JA, Serquiz AC, Silva PF, Barbosa PB, Sampaio TB, Araújo Junior RF, Oliveira AS, Machado RJ, Maciel BL, Uchôa AF, Santos EA, Morais AH. Trypsin inhibitor from tamarindus indica L. seeds reduces weight gain and food consumption and increases plasmatic cholecystokinin levels. Clinics (Sao Paulo). 2015 Feb;70(2):136-43. doi: 10.6061/clinics/2015(02)11. PMID: 25789523; PMCID: PMC4351314.
[vi] Vagadia BH, Vanga SK, Raghavan V. Inactivation methods of soybean trypsin inhibitor – A Review. Trends in Food Science & Technology. 2017 Jun;64:115–25. doi:10.1016/j.tifs.2017.02.003
[vii] Udani J, Tan O, Molina J. Systematic Review and Meta-Analysis of a Proprietary Alpha-Amylase Inhibitor from White Bean (Phaseolus vulgaris L.) on Weight and Fat Loss in Humans. Foods. 2018 Apr 20;7(4):63. doi: 10.3390/foods7040063. PMID: 29677119; PMCID: PMC5920428.
[viii] Wu, X., Xu, X., Shen, J., Perricone, N. V., & Preuss, H. G. (2010). Enhanced weight loss from a dietary supplement containing standardized Phaseolus vulgaris extract in overweight men and women. Journal of Applied Research, 10(2), 73+. https://link.gale.com/apps/doc/A234935974/AONE?u=anon~317c2321&sid=googleScholar&xid=61ff244c
[ix] Wang S, Guo C, Xing Z, Li M, Yang H, Zhang Y, et al. Dietary intervention with α-amylase inhibitor in white kidney beans added yogurt modulated gut microbiota to adjust blood glucose in mice. Frontiers in Nutrition. 2021 Oct 12;8. doi:10.3389/fnut.2021.664976
[x] Weight loss supplements market report, 2021-2028 [Internet]. [cited 2024 Mar 4]. Available from: https://www.grandviewresearch.com/industry-analysis/weight-loss-supplements-market-report
[xi] Singh M, Thrimawithana T, Shukla R, Adhikari B. Managing obesity through natural polyphenols: A Review. Future Foods. 2020 Sept;1–2:100002. doi:10.1016/j.fufo.2020.100002